Other Bids VA $500K+ Reviewed

Protein ENGineering (PENG)

Defense Advanced Research Projects Agency (DARPA)

ARLINGTON, VA

protein engineering organoid research cellular biotechnology therapeutic platform development $500K+

Posted Aug 7, 2026

Due Oct 19, 2026

Description

DARPA is soliciting proposals for the Protein ENGineering (PENG) program to develop a multifunctional, target-agnostic platform for precise, programmable editing of endogenous proteins. The proposed platform is to integrate modular targeting, generalizable effector chemistries, and multiplexed controls, using approaches such as splicing, ligation, and co-translational techniques, with validation in high-fidelity cellular models such as organoids.

Relevant to the healthcare sector

Curated for medical & healthcare suppliers

Why we classified this as medical

This DARPA solicitation concerns advanced biomedical research to edit endogenous proteins in cells and organoids, making it relevant to biotechnology and therapeutic R&D vendors. However, it does not procure a clinical product, diagnostic service, pharmaceutical, or direct patient-care service, so it remains below the clearly medical range.

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